Magnitude of Meconium Aspiration Syndrome and Associated Factors Among Neonates Admitted to Neonatal Intensive Care Unit of Arsi Zone, Ethiopia; 2023

Teshome Ketema Sime; Teklu Gemechu; Kumera Bekele; Dejene Hailu; Elias Geneti

doi:doi:10.11648/j.ajp.20261201.14

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Magnitude of Meconium Aspiration Syndrome and Associated Factors Among Neonates Admitted to Neonatal Intensive Care Unit of Arsi Zone, Ethiopia; 2023

Teshome Ketema Sime^*

, Teklu Gemechu, Kumera Bekele, Dejene Hailu, Elias Geneti

Published in American Journal of Pediatrics (Volume 12, Issue 1)

Received: 18 December 2025 Accepted: 23 January 2026 Published: 9 February 2026

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Abstract

Background: Meconium aspiration syndrome is a serious, potentially fatal condition that affects newborns with a high morbidity and mortality and continues to be a major contributor to neonatal respiratory distress, often resulting in respiratory failure and even death. Globally, around 4–22% of all births have meconium-stained amniotic fluid, and in 3-12% of those infants delivered eventually acquire meconium aspiration syndrome. Therefore, this study is aimed to assess the magnitude of meconium aspiration syndrome and associated factors among neonates admitted to neonatal intensive care units of public hospital in Arsi zone, Oromia, Ethiopia, 2023. Methods: An institutional-based cross-sectional study design was used to collect data among 345 participants from June 30 to August 30, 2023 in selected public hospitals of Arsi zone. The data was gathered through caregiver interviews and chart review. Systematic random sampling technique was used to select study participants. The collected data was entered into Epi-Data version 3.1 and exported to SPSS version 25. To analyze the data, first bivariable, then multivariable logistic regression model was used and those variables with p < 0.05 were considered to be statistically significant. The model of fitness was tested using the Hosmer-Lemesho goodness of fit. Result: The magnitude of meconium aspiration syndrome in this study was found to be 26.0%. Post-term (AOR=3.34 95% CI (1.41, 7.98)), Antepartum hemorrhage (AOR=7.72 95% CI (2.82, 21.15)), Preeclampsia (AOR=6.55 95% CI (2.63, 16.29)), Premature rupture of membrane (AOR=2.41 95% CI (1.32, 4.41)), First minute Apgar score < 7 (AOR=2.69 95% CI (1.36, 5.33)) were found to be significantly associated with meconium aspiration syndrome. Conclusion: The magnitude of meconium aspiration was moderate as compared to previous study. Post term, Antepartum hemorrhage, Preeclampsia, Premature rupture of membrane, First minute APGAR score < 7 were significantly associated with meconium aspiration syndrome. Therefore, early diagnoses and management of those factors are important for reducing the occurrences of meconium aspiration syndrome.

Published in	American Journal of Pediatrics (Volume 12, Issue 1)
DOI	10.11648/j.ajp.20261201.14
Page(s)	20-33
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2026. Published by Science Publishing Group

Keywords

Arsi, Magnitude, Meconium, Post Term

References

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APA Style

Sime, T. K., Gemechu, T., Bekele, K., Hailu, D., Geneti, E. (2026). Magnitude of Meconium Aspiration Syndrome and Associated Factors Among Neonates Admitted to Neonatal Intensive Care Unit of Arsi Zone, Ethiopia; 2023. American Journal of Pediatrics, 12(1), 20-33. https://doi.org/10.11648/j.ajp.20261201.14

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ACS Style

Sime, T. K.; Gemechu, T.; Bekele, K.; Hailu, D.; Geneti, E. Magnitude of Meconium Aspiration Syndrome and Associated Factors Among Neonates Admitted to Neonatal Intensive Care Unit of Arsi Zone, Ethiopia; 2023. Am. J. Pediatr. 2026, 12(1), 20-33. doi: 10.11648/j.ajp.20261201.14

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AMA Style

Sime TK, Gemechu T, Bekele K, Hailu D, Geneti E. Magnitude of Meconium Aspiration Syndrome and Associated Factors Among Neonates Admitted to Neonatal Intensive Care Unit of Arsi Zone, Ethiopia; 2023. Am J Pediatr. 2026;12(1):20-33. doi: 10.11648/j.ajp.20261201.14

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@article{10.11648/j.ajp.20261201.14,
  author = {Teshome Ketema Sime and Teklu Gemechu and Kumera Bekele and Dejene Hailu and Elias Geneti},
  title = {Magnitude of Meconium Aspiration Syndrome and Associated Factors Among Neonates Admitted to Neonatal Intensive Care Unit of Arsi Zone, Ethiopia; 2023},
  journal = {American Journal of Pediatrics},
  volume = {12},
  number = {1},
  pages = {20-33},
  doi = {10.11648/j.ajp.20261201.14},
  url = {https://doi.org/10.11648/j.ajp.20261201.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajp.20261201.14},
  abstract = {Background: Meconium aspiration syndrome is a serious, potentially fatal condition that affects newborns with a high morbidity and mortality and continues to be a major contributor to neonatal respiratory distress, often resulting in respiratory failure and even death. Globally, around 4–22% of all births have meconium-stained amniotic fluid, and in 3-12% of those infants delivered eventually acquire meconium aspiration syndrome. Therefore, this study is aimed to assess the magnitude of meconium aspiration syndrome and associated factors among neonates admitted to neonatal intensive care units of public hospital in Arsi zone, Oromia, Ethiopia, 2023. Methods: An institutional-based cross-sectional study design was used to collect data among 345 participants from June 30 to August 30, 2023 in selected public hospitals of Arsi zone. The data was gathered through caregiver interviews and chart review. Systematic random sampling technique was used to select study participants. The collected data was entered into Epi-Data version 3.1 and exported to SPSS version 25. To analyze the data, first bivariable, then multivariable logistic regression model was used and those variables with p Result: The magnitude of meconium aspiration syndrome in this study was found to be 26.0%. Post-term (AOR=3.34 95% CI (1.41, 7.98)), Antepartum hemorrhage (AOR=7.72 95% CI (2.82, 21.15)), Preeclampsia (AOR=6.55 95% CI (2.63, 16.29)), Premature rupture of membrane (AOR=2.41 95% CI (1.32, 4.41)), First minute Apgar score Conclusion: The magnitude of meconium aspiration was moderate as compared to previous study. Post term, Antepartum hemorrhage, Preeclampsia, Premature rupture of membrane, First minute APGAR score < 7 were significantly associated with meconium aspiration syndrome. Therefore, early diagnoses and management of those factors are important for reducing the occurrences of meconium aspiration syndrome.},
 year = {2026}
}

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TY  - JOUR
T1  - Magnitude of Meconium Aspiration Syndrome and Associated Factors Among Neonates Admitted to Neonatal Intensive Care Unit of Arsi Zone, Ethiopia; 2023
AU  - Teshome Ketema Sime
AU  - Teklu Gemechu
AU  - Kumera Bekele
AU  - Dejene Hailu
AU  - Elias Geneti
Y1  - 2026/02/09
PY  - 2026
N1  - https://doi.org/10.11648/j.ajp.20261201.14
DO  - 10.11648/j.ajp.20261201.14
T2  - American Journal of Pediatrics
JF  - American Journal of Pediatrics
JO  - American Journal of Pediatrics
SP  - 20
EP  - 33
PB  - Science Publishing Group
SN  - 2472-0909
UR  - https://doi.org/10.11648/j.ajp.20261201.14
AB  - Background: Meconium aspiration syndrome is a serious, potentially fatal condition that affects newborns with a high morbidity and mortality and continues to be a major contributor to neonatal respiratory distress, often resulting in respiratory failure and even death. Globally, around 4–22% of all births have meconium-stained amniotic fluid, and in 3-12% of those infants delivered eventually acquire meconium aspiration syndrome. Therefore, this study is aimed to assess the magnitude of meconium aspiration syndrome and associated factors among neonates admitted to neonatal intensive care units of public hospital in Arsi zone, Oromia, Ethiopia, 2023. Methods: An institutional-based cross-sectional study design was used to collect data among 345 participants from June 30 to August 30, 2023 in selected public hospitals of Arsi zone. The data was gathered through caregiver interviews and chart review. Systematic random sampling technique was used to select study participants. The collected data was entered into Epi-Data version 3.1 and exported to SPSS version 25. To analyze the data, first bivariable, then multivariable logistic regression model was used and those variables with p Result: The magnitude of meconium aspiration syndrome in this study was found to be 26.0%. Post-term (AOR=3.34 95% CI (1.41, 7.98)), Antepartum hemorrhage (AOR=7.72 95% CI (2.82, 21.15)), Preeclampsia (AOR=6.55 95% CI (2.63, 16.29)), Premature rupture of membrane (AOR=2.41 95% CI (1.32, 4.41)), First minute Apgar score Conclusion: The magnitude of meconium aspiration was moderate as compared to previous study. Post term, Antepartum hemorrhage, Preeclampsia, Premature rupture of membrane, First minute APGAR score < 7 were significantly associated with meconium aspiration syndrome. Therefore, early diagnoses and management of those factors are important for reducing the occurrences of meconium aspiration syndrome.
VL  - 12
IS  - 1
ER  -

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Teshome Ketema Sime

Department of Midwifery, Salale University, Fiche, Ethiopia

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http://orcid.org/0009-0002-0936-5674
Teklu Gemechu

Department of Nursing, Salale University, Fiche, Ethiopia

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Kumera Bekele

Department of Nursing, Salale University, Fiche, Ethiopia

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Dejene Hailu

Department of Nursing, Salale University, Fiche, Ethiopia

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Elias Geneti

Department of Nursing, Salale University, Fiche, Ethiopia

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Sime, T. K., Gemechu, T., Bekele, K., Hailu, D., Geneti, E. (2026). Magnitude of Meconium Aspiration Syndrome and Associated Factors Among Neonates Admitted to Neonatal Intensive Care Unit of Arsi Zone, Ethiopia; 2023. American Journal of Pediatrics, 12(1), 20-33. https://doi.org/10.11648/j.ajp.20261201.14

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Sime, T. K.; Gemechu, T.; Bekele, K.; Hailu, D.; Geneti, E. Magnitude of Meconium Aspiration Syndrome and Associated Factors Among Neonates Admitted to Neonatal Intensive Care Unit of Arsi Zone, Ethiopia; 2023. Am. J. Pediatr. 2026, 12(1), 20-33. doi: 10.11648/j.ajp.20261201.14

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AMA Style

Sime TK, Gemechu T, Bekele K, Hailu D, Geneti E. Magnitude of Meconium Aspiration Syndrome and Associated Factors Among Neonates Admitted to Neonatal Intensive Care Unit of Arsi Zone, Ethiopia; 2023. Am J Pediatr. 2026;12(1):20-33. doi: 10.11648/j.ajp.20261201.14

Copy | Download

@article{10.11648/j.ajp.20261201.14,
  author = {Teshome Ketema Sime and Teklu Gemechu and Kumera Bekele and Dejene Hailu and Elias Geneti},
  title = {Magnitude of Meconium Aspiration Syndrome and Associated Factors Among Neonates Admitted to Neonatal Intensive Care Unit of Arsi Zone, Ethiopia; 2023},
  journal = {American Journal of Pediatrics},
  volume = {12},
  number = {1},
  pages = {20-33},
  doi = {10.11648/j.ajp.20261201.14},
  url = {https://doi.org/10.11648/j.ajp.20261201.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajp.20261201.14},
  abstract = {Background: Meconium aspiration syndrome is a serious, potentially fatal condition that affects newborns with a high morbidity and mortality and continues to be a major contributor to neonatal respiratory distress, often resulting in respiratory failure and even death. Globally, around 4–22% of all births have meconium-stained amniotic fluid, and in 3-12% of those infants delivered eventually acquire meconium aspiration syndrome. Therefore, this study is aimed to assess the magnitude of meconium aspiration syndrome and associated factors among neonates admitted to neonatal intensive care units of public hospital in Arsi zone, Oromia, Ethiopia, 2023. Methods: An institutional-based cross-sectional study design was used to collect data among 345 participants from June 30 to August 30, 2023 in selected public hospitals of Arsi zone. The data was gathered through caregiver interviews and chart review. Systematic random sampling technique was used to select study participants. The collected data was entered into Epi-Data version 3.1 and exported to SPSS version 25. To analyze the data, first bivariable, then multivariable logistic regression model was used and those variables with p Result: The magnitude of meconium aspiration syndrome in this study was found to be 26.0%. Post-term (AOR=3.34 95% CI (1.41, 7.98)), Antepartum hemorrhage (AOR=7.72 95% CI (2.82, 21.15)), Preeclampsia (AOR=6.55 95% CI (2.63, 16.29)), Premature rupture of membrane (AOR=2.41 95% CI (1.32, 4.41)), First minute Apgar score Conclusion: The magnitude of meconium aspiration was moderate as compared to previous study. Post term, Antepartum hemorrhage, Preeclampsia, Premature rupture of membrane, First minute APGAR score < 7 were significantly associated with meconium aspiration syndrome. Therefore, early diagnoses and management of those factors are important for reducing the occurrences of meconium aspiration syndrome.},
 year = {2026}
}

Copy | Download

TY  - JOUR
T1  - Magnitude of Meconium Aspiration Syndrome and Associated Factors Among Neonates Admitted to Neonatal Intensive Care Unit of Arsi Zone, Ethiopia; 2023
AU  - Teshome Ketema Sime
AU  - Teklu Gemechu
AU  - Kumera Bekele
AU  - Dejene Hailu
AU  - Elias Geneti
Y1  - 2026/02/09
PY  - 2026
N1  - https://doi.org/10.11648/j.ajp.20261201.14
DO  - 10.11648/j.ajp.20261201.14
T2  - American Journal of Pediatrics
JF  - American Journal of Pediatrics
JO  - American Journal of Pediatrics
SP  - 20
EP  - 33
PB  - Science Publishing Group
SN  - 2472-0909
UR  - https://doi.org/10.11648/j.ajp.20261201.14
AB  - Background: Meconium aspiration syndrome is a serious, potentially fatal condition that affects newborns with a high morbidity and mortality and continues to be a major contributor to neonatal respiratory distress, often resulting in respiratory failure and even death. Globally, around 4–22% of all births have meconium-stained amniotic fluid, and in 3-12% of those infants delivered eventually acquire meconium aspiration syndrome. Therefore, this study is aimed to assess the magnitude of meconium aspiration syndrome and associated factors among neonates admitted to neonatal intensive care units of public hospital in Arsi zone, Oromia, Ethiopia, 2023. Methods: An institutional-based cross-sectional study design was used to collect data among 345 participants from June 30 to August 30, 2023 in selected public hospitals of Arsi zone. The data was gathered through caregiver interviews and chart review. Systematic random sampling technique was used to select study participants. The collected data was entered into Epi-Data version 3.1 and exported to SPSS version 25. To analyze the data, first bivariable, then multivariable logistic regression model was used and those variables with p Result: The magnitude of meconium aspiration syndrome in this study was found to be 26.0%. Post-term (AOR=3.34 95% CI (1.41, 7.98)), Antepartum hemorrhage (AOR=7.72 95% CI (2.82, 21.15)), Preeclampsia (AOR=6.55 95% CI (2.63, 16.29)), Premature rupture of membrane (AOR=2.41 95% CI (1.32, 4.41)), First minute Apgar score Conclusion: The magnitude of meconium aspiration was moderate as compared to previous study. Post term, Antepartum hemorrhage, Preeclampsia, Premature rupture of membrane, First minute APGAR score < 7 were significantly associated with meconium aspiration syndrome. Therefore, early diagnoses and management of those factors are important for reducing the occurrences of meconium aspiration syndrome.
VL  - 12
IS  - 1
ER  -

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